Biomonitoring of Oxidative DNA Damage in Traffic Policemen Exposed to Urban Air Pollution

Ultrafine particulate matter and high-level benzene urban air pollution in relation to oxidative DNA damage.

Air pollution, containing high-level of ultrafine particles (UFP) and benzene, is a prominent environmental health problem in many cities of the World. We investigated the level of oxidative DNA damage in mononuclear blood cells (MNBC) by the comet assay as DNA strand breaks (SB) and formamidopyrimidine DNA glycosylase (FPG) sensitive sites in residents from three urban locations in Cotonou, Be...

Comparative Studies between Aged Controlled Normal People and the Traffic Policemen Exposed to Air Pollution with the Comet Assay

Modelling Urban Traffic Air Pollution Dispersion

The prime aim of this research is to support decision making, e.g., air quality impact analysis, human health assessment, through spatially modelling traffic-induced air pollution dispersion in urban areas at street level. Based on the information needed in decision making, a framework for a street level air quality decision support system is established, which is composed of basically three pa...

Traffic-Related Air Pollution and DNA Damage: A Longitudinal Study in Taiwanese Traffic Conductors

BACKGROUND There is accumulating epidemiologic evidence that exposure to traffic-related air pollutants, including particulate matter (PM) and polyaromatic hydro carbons (PAHs), plays a role in etiology and prognosis of a large scale of illnesses, although the role of specific causal agents and underlying mechanisms for different health outcomes remains unknown. OBJECTIVE Our general objectiv...

Oxidative Damage to DNA and Lipids as Biomarkers of Exposure to Air Pollution

BACKGROUND Air pollution is thought to exert health effects through oxidative stress, which causes damage to DNA and lipids. OBJECTIVE We determined whether levels of oxidatively damaged DNA and lipid peroxidation products in cells or bodily fluids from humans are useful biomarkers of biologically effective dose in studies of the health effects of exposure to particulate matter (PM) from comb...